Vitamin D: Structure and mechanism of action

Vitamin D has received more attention in recent years as a result of the resurgence vitamin deficiency and rickets global health issue, well compelling evidence laboratory indicating that 1,25-dihydroxy D3 [1,25(OH)2D3], hormonally active form D, generates several extraskeletal biological responses such inhibition breast, colon, prostate cancer cell progression; effects on cardiovascular system; protects against. This review covers our present knowledge its bioactivation, fresh findings have altered understanding activity both classical nonclassical target tissues. page also assesses D's alleged involvement health, provides an overview 1,25(OH)2D3 analogs been created, highlights unanswered problems.